The spectrum of phytoestrogens in nature: our knowledge is expanding

Paraskevi Moutsatsou

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The classical phytoestrogens, so far known, constitute a group of plant-derived compounds which include mainly isoflavones, lignans, coumestanes, stilbenes and the flavonoids quercetin and kaempherol. The discovery of many more novel estrogen-like compounds in the plant kingdom demonstrates that the spectrum of phytoestrogens in nature is expanding …

Metformin: Its emerging role in oncology

Dragan Micic, Goran Cvijovic, Vladimir Trajkovic, Leonidas H. Duntas, Snezana Polovina

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Metformin is considered, in conjunction with lifestyle modification, as a first-line treatment modality for type 2 diabetes mellitus (DM). Recently, several clinical studies have reported reduced incidence of neoplastic diseases in DM type 2 patients treated with metformin, as compared to diet or other antidiabetic agents …