George Koukoulis, Antonis Polymeris, Ioanna Tzavara, Dimitrios Pappas, Nicke Thalassinos
Atrial Natriuretic Peptide (ANP) is a hormone produced by cardiac atrial myocytes. Thyroid hormones may affect its release. The aim of this study was to analyze the effect of hyper and hypothyroidism on the secretion of ANP and its relationship with the changes of the renin-angiotensin-aldosterone system. Plasma ANP concentration as well as plasma renin activity (PRA) and aldosterone …
Maria Bougoulia, Athanassios Triantos, George Koliakos
OBJECTIVE: To evaluate the levels of Interleukin-6 (IL-6), glutathione peroxidase and isoprostane in obese women and their association with markers of cardiovascular risk factors before and after weight loss. DESIGN: 36 healthy obese women of reproductive age (group A: age (mean ±SD) 35.4 ± 9.2 years, Body Mass Index (BMI) 38.5±7 kg/m2) and 30 healthy, normal weight women …
Ariachery C. Ammini, Saptarshi Bhattacharya, Jaya Praksh Sahoo, Jim Philip, Nikhil Tandon, Ravinder Goswami, Viveka P. Jyotsna, Rajesh Khadgawat, Sunil Chumber, Aashu Seth, Asis K. Karak, Bhawani S. Sharma, Poodipedi Sarat Chandra, Ashish Suri, Manish S. Sharma, Shashank S. Kale, Manmohan Singh
OBJECTIVE: To analyze the therapeutic results of intervention and the factors affecting the outcome of patients with Cushing’s disease (CD) cared for at the All Indian Institute of Medical Science (AIIMS), New Delhi. DESIGN. Patients with Cushing’s disease treated at a teritiary care centre from January 2000 to December 2009 were prospectively studied …
Tommaso Aversa, Mariacarolina Salerno, Giorgio Radetti, Maria Felicia Faienza, Lorenzo Iughetti, Andrea Corrias, Barbara Predieri, Alessandro Mussa, Silvestro Mirabelli, Filippo De Luca, Malgorzata Wasniewska
BACKGROUND: Studies concerning presentation and evolution over time of Hashimoto’s thyroiditis (HT) in children with Down’s syndrome (DS) are few, are based on limited study populations and do not include control HT groups without DS. The aim of this multicenter study was to shed further light on the relationships between DS and HT in childhood …
Ioannis Ilias, Maria Alevizaki, Elli Lakka-Papadodima, Demetrios A. Koutras
Thyroid cancer (TC) is a relatively rare neoplasia, accounting for 0.35%-0.38% of total deaths due to cancer in Greece. Environmental/nutritional factors are considered to play a role in its pathogenesis. The aim of this retrospective review of patients’ histories from three of the largest specialized centers in southern Greece, from 1963 to 2000…
George Vlotides, Roland Gaertner, Matthias W.A. Angstwurm
OBJECTIVE: Modulatory effects of estrogens on both the immune and the coagulation system are only partially understood. In severe infections high estrogen levels have been observed both in men and postmenopausal women and are associated with increased mortality. Monocyte-derived tissue factor (TF) expression can activate the coagulation system and worsen the course of severe infection…
Christakou Charikleia, Economou Frangiskos, Livadas Sarantis, Piperi Christina, Adamopoulos Christos, Marinakis Evangelos, Diamanti-Kandarakis Evanthia
OBJECTIVE: Advanced glycation end products (AGEs) activate the intracellular Nuclear Factor-κB pathway in endothelial cells, leading to production of endothelin-1 (ET-1), a peptide which causes endothelial dysfunction. The aim of the present study was to assess ΕΤ-1 and AGEs levels in women with polycystic ovary syndrome …
Djuro Macut, Ivana Božić Antić, Jelica Bjekić-Macut, Dimitrios Panidis, Konstantinos Tziomalos, Danijela Vojnović Milutinović, Olivera Stanojlović, Biljana Kastratović-Kotlica, Milan Petakov, Nataša Milić
OBJECTIVE: There is a need for a simple and accurate method for the assessment of cardiovascular risk in polycystic ovary syndrome (PCOS). Lipid accumulation product (LAP) is based on the assessment of waist circumference and serum triglycerides that yield an estimation of lipid overaccumulation. We aimed to determine whether LAP is associated with metabolic syndrome (MetS) in Caucasian women with PCOS …
Odysseas Gregoriou,George Christodoulakos, Charalambos Siristatidis, Socrates Conidaris, Evangelia Kouskouni, George Creatsas
Objective: The purpose of this study was to examine the effects of Hormone Replacement Therapy (HRT) on plasma lipoprotein levels, bone mass and the endometrium. Methods: Thirty healthy women were enrolled in the study for climacteric symptoms and received a combination of 17β-estradiol and norethisterone acetate continuously for 2 years …
Kyratsoula Pantsiotou
OBJECTIVE: Longitudinal data on boys’ puberty evolution are not available in Greece and very few such studies have been reported world-wide. We present data from a longitudinal study on height, weight, BMI and age at the different pubertal stages in Greek boys. DESIGN: At the start of the study 204 prepubertal boys aged 8-10 years …
Ekaterini Koiou, Konstantinos Tziomalos, Ilias Katsikis, Konstantinos Dinas, Elena A. Tsourdi, Eleni A. Kandaraki, Dimitrios Delkos, Efstathios Papadakis, Dimitrios Panidis
OBJECTIVE: We aimed to assess plasma Von Willebrand factor (vWF) levels in women with polycystic ovary syndrome (PCOS) and to compare these levels among the different PCOS phenotypes. DESIGN: We studied 140 women with PCOS and 40 age and body mass index (BMI)- matched healthy women …
Giovanni Corona, Silvia Bianchini, Alessandra Sforza, Linda Vignozzi, Mario Maggi
There is evidence demonstrating that sexual complaints represent the most specific symptoms associated with late onset hypogonadism, while central obesity is the most specific sign. In obese men, hypogonadism can further worsen the metabolic profile and increase abdominal fat …
George N. Zografos, Athina Markou, Chrisanthi Ageli, Nikos Kopanakis, Spiros Koutmos, Gregory Kaltsas, George Piaditis, George I. Papastrati
OBJECTIVE. Laparoscopic adrenalectomy has rapidly replaced open adrenalectomy as the procedure of choice for benign adrenal tumors. The aim of this study was to evaluate the short- and long-term results of 100 consecutive laparoscopic and open adrenalectomies performed during a period of 8.5 years in our Surgical Unit…
Ioannis Ilias, Konstantinos Stamoulis, Apostolos Armaganidis, Panagiotis Lyberopoulos, Marinella Tzanela, Stylianos Orfanos, Maria Theodorakopoulou, Stylianos Tsagarakis, Ioanna Dimopoulou
OBJECTIVE: To evaluate whether tentative prognostic models for intensive care unit survival of multiple trauma patients could be improved by including endocrine parameters. DESIGN: Prospective study. Patients: Eighty-three male and 11 female multiple trauma patients…
Georgios A. Christou, Constantinos C. Tellis, Moses S. Elisaf, Alexandros D. Tselepis, Dimitrios N. Kiortsis
OBJECTIVE: The investigation of the relationship between high density lipoprotein (HDL) and adiponectin. DESIGN: Thirty-seven obese or overweight [body mass index ≥27 Kg/m2], hypertriglyceridemic patients underwent one of the following interventions for 3 months …
Marianna Katrinaki, Marilena Kampa, Andrew Margioris, Elias Castanas, Niki Malliaraki
OBJECTIVE: The determination of the normal range of 25-hydroxyvitamin D [25-(OH)D], though currently based on suppression of PTH levels, still remains a controversial issue. The 25-(OH)D levels exhibit gender and seasonal variability, the latter attributed in part to changes of insolation. DESIGN: The aim of this cross-sectional study was to estimate the levels of 25-(OH)D on the island of Crete …
Teresa Zak, Anna Noczýnska, Renata Wasikowa, Urszula Zaleska-Dorobisz, Anna Golenko
The aim of the study was to analyze data related to chronic autoimmune thyroid disease at diagnosis and at follow-up of children and adolescents in Lower Silesia in the years 1999-2004. Age, gender, incidence of thyroid disease in the family, clinical presentation, hormonal findings, levels of thyroid antibodies, results of ultrasonography, and fine needle aspiration biopsy (FNAB) were recorded …
Evangelos Karanikas, Faidon Harsoulis, Ioannis Giouzepas, Ioannis Griveas
OBJECTIVE: Psychocutaneous diseases constitute a large proportion of psychosomatic disorders, with psoriasis being one of the most typical cases. Though alteration of Hypothalamic-Pituitary-Adrenal (HPA) axis function has been suggested as underlying several psychiatric disorders and psychosomatic diseases, there is little evidence of reduced response of the HPA axis in psoriasis after psychosocially …
Cristiana Cipriani, Elisabetta Romagnoli, Vincenzo Carnevale, Ida Raso, Addolorata Scarpiello, Maurizio Angelozzi, Andrea Tancredi, Stefania Russo, Federica De Lucia, Jessica Pepe, Salvatore Minisola
OBJECTIVE: The aim of this work was to examine the effects of age and menopause on muscle strength and on the muscle-bone interaction. DESIGN: One hundred ninety-four healthy women (mean age 49.8 ± 12.6 SD years) were assessed …
Dohee Kim
OBJECTIVE: The association of low vitamin D status with autoimmune thyroid disease (AITD), which includes Hashimoto’s thyroiditis (HT) and Graves’ disease (GD), is controversial. The aim of this study was to investigate the correlation between vitamin D insufficiency and AITD, HT, and GD. DESIGN: Our cross-sectional study included patients …