Ioannis Karamouzis, Dimitrios Grekas, Michael Karamouzis, Athanasios Triantos, Svetla Vasileva-Staikova, Dimitrios Kovachev, Afroditi Dimitriadou
The concentration of 8-iso-prostaglandin-F2· (8-iso-PGF2α in biological fluids has been considered as the most reliable biochemical index of the lipid peroxidation and oxidative stress in patients with several pathological conditions including end stage renal failure …
Thalia Bei, Constantinos Tilkeridis, Stavros Garantziotis, Sosipatros A. Boikos, Konstantinos Kazakos, Constantinos Simopoulos, Constantine A. Stratakis
OBJECTIVE: We recently reported the association of the Sp1 site polymorphism of the COL1A1 gene with lumbar disk disease (LDD). In the present study we searched for a different polymorphism of the COL1A1 gene (which is usually not in linkage disequilibrium with the Sp1 site) in subjects with LDD…
Amela Lolic, Νenad Prodanovic
Objective: A survey related to iodine deficiency in the Republic of Srpska was first conducted in 1999 and resulted in the adoption of regulations concerning the quality of salt for human consumption. In order to reassess iodine status, we conducted the Republic of Srpska Iodine Deficiency Survey in 2006 …
Ines Zendah, Hafaoua Daghfous, Sonia Ben Mrad, Fatma Tritar
Thyroid tuberculosis is a rare disease even in countries in which tuberculosis (TB) constitutes an endemic disorder. The diagnosis is often difficult as the clinical presentation has no distinct characteristics. We report a 47-year-old woman who presented with a painful nodular swelling of the neck, confirmed by physical examination and sweating…
Serkan Yener, Abdurrahman Comlekci, Baris Akinci, Pinar Akan, Tevfik Demir, Firat Bayraktar, Sena Yesil
OBJECTIVE: a)To determine serum Transforming Growth Factor-beta 1 (TGF-β1) levels in patients with type 2 diabetes who do not have diabetes related complications and in healthy controls, b) to evaluate the effects of metformin and rosiglitazone on TGF-β1 levels …
Mehmet Kirnap, Hulusi Atmaca, Fatih Tanriverdi, Osman Ozsoy, Kursad Unluhizarci, Fahrettin Kelestimur
OBJECTIVE: To investigate the hypothalamic-pituitary-adrenal (HPA) axis via the insulin-tolerance test (ITT), standard-dose (250 μg) ACTH test (SDT) and low-dose (1 μg) ACTH test (LDT) in patients with ankylosing spondylitis (AS). DESIGN: The study group included 13 male patients with AS who were diagnosed according to the Modified New York criteria …
Gideon de Sousa, Rainer Wunsch, Werner Andler
We report the findings and clinical course of ten girls aged 0.2 to 6.3 years with precocious pseudopuberty due to autonomous ovarian cysts. We found elevated oestrogen levels in five patients and failure of gonadotropin response to GnRH stimulation in four patients during the first episode, of the disease …
Assimina Galli-Tsinopoulou, Eleftheria Emmanouilidou, Paraskevi Karagianni, Maria Grigoriadou, John Kirkos, George S. Varlamis
Silver Russell Syndrome (SRS) is a rare condition (1/3000 – 1/100,000 newborns). We present a female infant with SRS, cardiac malposition and asymmetric enlargement of the clitoris. She is the first child of Greek nonconsanguinous parents, born at 38 weeks gestation …
Mehmet Uludag, Gurkan Yetkin, Bulent Citgez, Adnan Isgor, Tulay Basak
The malignancy risk is low in hot thyroid nodules verified by scintigraphy. We present a rare case of papillary carcinoma, initially treated as an autonomous hot nodule. Case report. A 36-year old male patient with a hot thyroid nodule and subclinical hyperthyroidism was treated with 10mCi 131I.
Basil Leoutsakos, Agnes Leoutsakos
Menelaos L. Batrinos
Contrary to the commonly held belief that in antiquity and as late as 1700 A.D. normal lifespan was about 35 years, there are indications that the ancient Greeks lived longer. In a study of all men of renown, living in the 5th and 4th century in Greece …
Selcuk Dagdelen, Mevlut Kurt, Kadriye Aydιn, Miyase Bayraktar
Severity of thiazolidinedione (Rosiglitazone)-induced fluid retention is linked almost exclusively to cardiac decompensation. We here report a 68-year old female with type 2 diabetes mellitus, in whom a life-threatening (anasarca type) acute pulmonary edema, induced by rosiglitazone plus insulin therapy …
Alexandra Chrisoulidou, Kalliopi Pazaitou-Panayiotou, Eleni Georgiou, Maria Boudina, George Kontogeorgos, Ioannis Iakovou, Ioannis Efstratiou, Frideriki Patakiouta, Iraklis Vainas
Ectopic production of CRH by a medullary thyroid carcinoma or its metastases is a rare cause of ectopic Cushing’s syndrome (ECS). We report a 45-year old male with medullary thyroid carcinoma (MTC), who, 24 years following the initial diagnosis …
Aristidis Diamantis, George Androutsos
In 1847 Felix-Archimede Pouchet effectively launched the study of the physiology of cytology. Now 160 years later, the authors briefly trace the development of hormonal cytology to our present knowledge and practice. In the course of the paper the contribution of George Papanicolaou is stressed because of his monumental contribution to a major segment of medical practice of great emotive import …
Stefanie Petzold, Alexandra Keller, Eberhardt Keller, Christof Meigen, Wolfgang Hirsch, Jürgen Kratzsch, Wieland Kiess, Roland Pfäffle
Combined pituitary hormone deficiency (CPHD) is a rare disorder resulting from impaired production of several pituitary hormones. This report describes the 30-year history of a patient who has apparently lived without a pituitary …
Eleanor Roderick, Niki Karavitaki, John AH Wass
The history of the management of craniopharyngiomas offers a comprehensive review of the exciting progress in neurosurgery, neuroimaging, neuroendocrinology and radiation oncology during the last century. In this historical note, we present the evolution in management of these most challenging of brain tumours, which, despite the substantial knowledge and expertise gained since the first attempt of surgical removal, remains a subject of considerable debate…